Posts tagged with "Sanofi"

Eli Lilly to cut prices of insulin drugs by 70%, cap patient costs at $35

March 2, 2023

Eli Lilly—facing pressure to curb diabetes-treatment costswill cut the list prices for its most commonly prescribed insulin products by 70% and take other steps to make it easier for patients to afford the drugs, reports The Wall Street Journal.

On Wednesday, March 1, the Indianapolis-based company announced that the 70% price cuts will take effect in the fourth quarter for Humalog and Humulin, its two biggest-selling insulin products.

The company also said that on May 1 it would reduce the list price of an unbranded insulin it sells to $25 a vial from $82 a vial—the lowest level for any insulin that diabetes patients take around mealtimes, and less than Lilly’s list price for a Humalog vial in 1999. And it plans to improve a program capping patients’ out-of-pocket costs at $35 a month.

“The aggressive price cuts we’re announcing today should make a real difference for Americans with diabetes,” said Lilly Chief Executive David Ricks.

Drugmakers—including Lilly, Novo Nordisk and Sanofi—substantially raised the prices for their insulin products during the 2010s. Now, the products cost hundreds of dollars a month. Humalog currently has a list price of $530 for a five-pack of injection pens and $274 for a vial; although Lilly said most people with commercial insurance and Medicare pay no more than $95 a month.

The manufacturers have said that, while list prices increased, they have had to pay larger rebates to companies that manage drug benefits.

Yet, because of the high prices, people without insurance or with high-deductible health plans can have trouble affording the products—forcing them to ration use.

To ease the burden, some U.S. states have enacted insulin-cost caps in recent years. Last year’s Inflation Reduction Act mandated that patients covered by the federal Medicare health-insurance program should pay no more than $35 a month in copays or other out-of-pocket costs for an insulin prescription.

In his State of the Union address in February, President Joe Biden called for that $35 monthly cap to be expanded beyond Medicare to include every diabetes patient.

In addition to reducing the list prices for its top-selling insulins, Lilly said it would introduce on April 1 a new insulin, named Rezvoglar, that is a copycat version of Sanofi’s Lantus insulin. Lilly will list its price at $92 for a five-pack of injection pens, a 78% discount to the list price for Lantus.

The company said it would make improvements to its program, introduced in 2020, to cap insulin out-of-pocket costs at $35 a month. Participating pharmacies will now implement that cap automatically when people with commercial insurance fill their prescriptions, rather than requiring people to present a Lilly savings card.

People without insurance can continue to cap monthly costs at $35 for Lilly insulin products by using a savings card that can be downloaded immediately online, the company said.

Research contact: @WSJ

NYT: President Trump has ‘financial interest’ in hydroxychloroquine manufacturer

April 8, 2020

For days, rumors have been rampant on social media—speculating that President Donald Trump is recommending (nay, hyping) the use of hydroxychloroquine as a potential cure for COVID-19 because he has invested in the company that manufactures the drug. Now, The New York Times confirms the scuttlebutt.

In fact, the Times reports, the president has a “small financial interest” in the maker of the anti-malarial drug that he has been touting as a “game changer” in treating coronavirus.

The news outlet notes that the president’s family trusts all have investments in a mutual fund whose largest holding is Sanofi, the Paris, France-based manufacturer of Plaquenil, the brand-name version of hydroxychloroquine.

Associates of the president, including Commerce Secretary Wilbur Ross, also have run funds that hold investments in the pharmaceutical firm.

Thus, it is a little less confounding that, over the past two weeks, Trump and his Fox News allies have aggressively promoted hydroxychloroquine as a potential coronavirus cure—despite strong pushback from top infectious-disease expert Dr. Anthony Fauci and others urging caution and noting that there currently is not enough evidence of the drug’s efficacy.

A case in point: President Trump made a rare appearance in the Situation Room on Sunday, April 5, as his pandemic task force was meeting, determined to talk about the anti-malaria medicine that he has aggressively promoted lately as a treatment for the coronavirus.

Once again, according to a person briefed on the session, the experts warned against overselling a drug yet to be proved a safe remedy, particularly for heart patients. “Yes, the heart stuff,” Trump acknowledged. Then he headed out to the cameras to promote it anyway. “So what do I know?” he conceded to reporters at his daily briefing. “I’m not a doctor. But I have common sense.”

Again and again, the president has made a passing reference to the dangerous side effects of the unproven drug, followed by a full-throated endorsement. “What do you have to lose?” he asked five times on Sunday.

Along the way, he has prompted an international debate about a drug that many doctors in New York and elsewhere have been trying on patients in desperation— even without conclusive scientific studies.

But Trump continues to push, the Times reports: At his briefing after the meeting, he said it was wrong to wait for the kind of study Dr. Fauci wanted. “We don’t have time,” the president said. “We don’t have two hours because there are people dying right now.”

Research contact: @nytimes

Lilly to offer insulin at 50% lower price in U.S. pharmacies

March 5, 2019

About 1.25 million Americans suffer from Type 1 diabetes—a serious condition in which the body fails to properly regulate blood sugar—and for them, buying insulin is a “do or die” decision.

Thus, when the price of prescription insulin at U.S. pharmacies began to rise rapidly within the past few years—more than tripling from $300 for a 90-day prescription to $1,000 or more today—they and their families began having to choose between other necessities and the price of the life-saving hormone.

N o generic version of the drug existed, and three manufacturers—Eli Lilly (Indianapolis), Sanofi (Paris), and Novo Nordisk (Bagsværd, Denmark)—control 99% of the market

Now, Eli Lilly has announced that it will step up to help patients nationwide-offering a 50% lower-priced generic version of Humalog (insulin lispro injection 100 units/mL) at pharmacies in the United States.

“We’ve engaged in discussions about the price of insulin with many different stakeholders in America’s health care system: people living with diabetes, caregivers, advocacy groups, health care professionals, payers, wholesalers, lawmakers, and leading health care scholars,” said Lilly’s CEO David A. Ricksin a company release, adding, “Solutions that lower the cost of insulin at the pharmacy have been introduced in recent months, but more people need help. We’re eager to bring forward a low-priced rapid-acting insulin.

“The significant rebates we pay on insulins do not directly benefit all patients. This needs to change,” Ricks said. “There are numerous ideas, including the rebate reform proposal from HHS. For people with diabetes, a lower-priced insulin can serve as a bridge that addresses gaps in the system until a more sustainable model is achieved.”

The lower-priced version will be called Insulin Lispro—the same molecule as Humalog—and will be available in vial and pen options. The list price of a single vial will be $137.35. The list price of a five-pack of KwikPens will be $265.20.

Vials and pens of the lower-priced insulin have been manufactured, and Lilly will now work with supply chain partners to make them available in pharmacies as quickly as possible. It will be made available as an authorized generic through a Lilly subsidiary, ImClone Systems.

Humalog also will remain available for people who want to continue accessing it through their current insurance plans. Introducing an alternative insulin option allows Lilly to provide a lower-priced insulin more quickly while providing payers time to renegotiate downstream contracts and adjust to new system economics.

“While this change is a step in the right direction, all of us in the health care community must do more to fix the problem of high out-of-pocket costs for Americans living with chronic conditions,” Ricks said. “We hope our announcement is a catalyst for positive change across the U.S. healthcare system.”

Lilly’s Insulin Lispro is one of many initiatives the company has introduced to deliver lower out-of-pocket options to people living with diabetes. After exploring the logistics and feasibility of an authorized generic, Lilly began preparing manufacturing, labeling, and shipping plans last year for the possibility of Lilly’s Insulin Lispro. People should call the Lilly Diabetes Solution Center at (833) 808-1234 to learn whether Lilly’s Insulin Lispro, or another option, is the best financial choice for them.

Humalog and Insulin Lispro are available by prescription only.

Research contact: @LillyPad